AwareofAware

Evolving news on the science, writing and thinking about Near Death Experiences (NDEs)

Two steps forward, one back

Samwise, once again, was first to spot this video. Initially there was some confusion as to whether it was recent or from last fall (2018), but Lucas, who watched the whole thing through, observed that he cited the pig study which was published two months ago. This presentation, made at Grand Rounds at NYU, was given in May this year, likely May 8th:

Link to Sam Parnia Grand Rounds May 2019

Now that I have had a chance to watch the entire video there are some very noteworthy points to make, in particular regarding the current status of the AWARE II study and a complete bombshell of a revelation which I will get to a bit later.

Firstly his presentation is a great review of the history and current state of resuscitation medicine, the area of expertise that Dr Parnia focuses most of his research work on. In particularly he spends time discussing the definition of death. Historically it was when the heart had stopped, there was no breathing and the pupils were fixed and dilated. With the advent of CPR in the 1950s this changed to about 5-10 minutes after the heart had stopped and CPR administered without the heart restarting. However, now it is clear that brain cells, the ones that will have the most significant impact on quality of life after resuscitation, could remain viable for many hours after “death” depending on the type of interventions administered from lowering body temperature to injecting magnesium. This is the area of medical research that Dr Parnia is devoting his greatest energy, and is already producing information that will help extend the period which a body remains viable after cardiac arrest. Bravo Dr Parnia, and we condone you for this great work. However, that is not the thing that gets us most excited on this blog/forum. So if you don’t want to learn all about that, fast forward to about 45 mins in when he starts talking about consciousness and death.

In this section he summarizes the findings of the AWARE I study, detailing the case of the man who had consciousness for 5 minutes and whose account was validated by attending Health Care Professionals (but not by the all important cards). That’s old news for us. He then mentions some of the materialist explanations of consciousness in general without getting into the details, and then the money slide:

half Money slide

This, according to Dr Parnia, is the enrollment status of AWARE II from April 2019. My first reaction was surprise that there had been so few new cases of patients surviving to discharge. In the presentation last year in which he showed data from March 2018, 38 patients had survived to discharge, this meant only 6 new cases. Then I started to look at the numbers more closely. Firstly the math is wrong. If you subtract the number who did not have return of spontaneous circulation (ROSC) from the total number recruited, you get 171 not 168. Big deal you say, well 171 happens to be the same number that had achieved ROSC on his slide from March 2018. Something fishy is going on. Either a lot more (all) patients are dying before discharge since March 2018, or they need to get a new statistician, or something else. It just doesn’t make any sense.

Then he threw this bombshell in:

whole Money slide

He casually stated that 10% of the patients who had a CA experienced seizure or seizure like EEG activity before ROSC. This is of course a potentially massive finding and contradicts much of what has been said before about NDEs. However, there is one key omission. There is no data on this slide showing numbers of patients who have an NDE, and even more importantly, there is no mention of correlation between reports of NDEs and this EEG activity. It is possibly the biggest teaser he has ever lobbed out to the NDE community.

Finally, Dr Parnia was scheduled to give another Grand rounds presentation focusing solely on consciousness during CA later in May. Maybe he shed more light on this discovery and managed to get the correct numbers on his slide…we won’t know until it is posted on the NYU site…Samwise will no doubt be the first to spot it.

Of course the skeptics will leap on the EEG activity, but until it is matched with reports of NDEs it is meaningless, and even then may be open to subjective interpretation. It is certainly hugely thought provoking, and at the same time frustrating until we learn more.

Time of death…

Partly due to the fact that the last post has nearly 300 comments and so it is good to start a fresh post, and partly because this really disturbing case study raises a question that is very relevant to the whole subject of NDEs, and therefore worth a discussion all of its own, I am posting this and asking the usual contributors and any new ones, to answer the question…”when are you actually dead?” And also what does this highly unusual case say about the relationship between consciousness and physical death, and NDEs in general:

Patient who remained conscious after heart stopped

“The authors conclude that the high level of patient awareness plus oxygen saturation and arterial gas being almost within the normal range throughout the 90 minutes of treatment indicate that peripheral and cerebral blood flow was good and the chest compressions were highly effective. They note that that even though the patient had a poor prognosis, the termination of CPR after 90 minutes raised ethical questions in the team as the individual was still conscious at the time.”

My thoughts, (the horror of the situation aside):

1. In the overwhelming majority of cases when the heart stops, normal “waking” consciousness is immediately lost. This is proven by the immediate and almost total loss of brain activity as measured by EEG. Prior to modern CPR this was historically defined as the point of death. This is why Dr Parnia refers to NDEs as ADEs…actual death experiences. In other words the patient is technically dead. In this case, the EEG probably showed activity associated with normal levels, although this is not mentioned. The patient experienced heart death but not brain death.

2. Death is a process, and as has been mentioned before, none more so than by Parnia himself, it is reversible, and using various methods, the point at which it can be fully reversed without any long term damage can be stretched beyond the several minutes mark. To me true physical death is the point past this. It is the point at which the cells have endured so much damage that the body, and especially the brain, is no longer able to function properly.

3. This case contradicts something that I had always thought was absolutely true…when the heart stops the conscious either shuts down completely, or starts to “detach itself” from the host as we believe is the case with NDEs. However, it appears that if CPR is immediate, and continuous blood flow is kept going, the conscious can somehow “be fooled” into believing that “its host” hasn’t died. What do these cases say about the nature of the connection between body and conscious? And for the skeptic do cases like this provide evidence against NDEs?

COOL news

OK, so Werner and Z both added links to Dr Parnia’s updated website.

Parnia’s research website

Z said there was nothing new, but buried in the list of studies there is something of great interest to those of us who have been following this field for the last 15 years, and it is this:

Conscious Awareness During Deep Hypothermic Circulatory Arrest

In our studies of cardiac arrest and its effects on consciousness, our data led us to hypothesize that higher-quality resuscitation is associated with a higher level of conscious awareness during cardiac arrest and resuscitation, which in turn is associated with improved survival, less severe brain injuries, and a smaller incidence of disorders of consciousness.

A novel way to study consciousness in a setting that biologically mimics clinical death besides cardiac arrest is to study patients undergoing deep hypothermic circulatory arrest (DHCA), a medical technique in which a patient’s temperature is cooled to approximately 20 degrees Celsius (68 degrees Fahrenheit), shutting down blood circulation and major organ function. This approach is often used by surgeons who need to operate on major blood vessels.

Because DHCA biologically mimics clinical death, but is very well controlled, it provides an excellent opportunity to study consciousness and awareness in a population, which unlike cardiac arrest, has a very high survival rate. We are developing new methods to determine what happens to consciousness before, during, and after this shutdown. We are using various technologies including portable EEG, cerebral oximetry, and visual and audio tools to test implicit and explicit learning as well as recall and memory.

This study complements our work in AWARE II, and we anticipate that we will discover exciting new aspects of the human mind.

This is basically very similar to the COOL study that was started in Montreal, but ended when the surgeon who performed the processes left. It is very exciting since there have been a number of reports over the years that have shown that doing this does indeed create NDE like experiences with OBEs. The key point, that Dr Parnia makes, is that the conditions are predictable and controlled. While there will be many more CAs than these procedures, there is also a much lower chance of survival or recall with a CA, so this route has a chance of producing results more consistently. Very excited to see this happening, and the fact that it is already ongoing, and may lead to results sooner rather than later. Case reports would be very interesting indeed.

Last off-topic post

As I mentioned in my last post, I would create one more post relating to my book, DNA: the elephant in the lab. This is short…a link to a 10 min video giving some background to the book:

YouTube video about origin of life

Next post will be back to NDEs.

DNA: the elephant in the lab – help needed!

Bespoke book cover art example from coverness.com

So this is what I have been up to for what seems like forever, but is actually only about 15 months. I know it’s not NDE related per se, however, it is directly relevant to the fundamental question of whether or not life is just a material thing. So it is in fact very relevant to the question of whether or not there is more to life than just eating, breeding and dying. This is also the question we look at with NDEs being evidence for the existence of a conscious that is not bound to the material realm. It does tie in…honest!

Anyway, I was “inspired” to write this after seeing the Governor General of Canada ridicule people who believe that life wasn’t the result of random processes (you tube link). This is a subject that I have some expertise in from my Ph.D. in organic medicinal chemistry where I messed around with nucleosides and amino acids, and my subsequent career in clinical research which involved drugs that affect DNA replication. I have also followed the literature on the origin of life over the years and read a number of books on the subject, but most of them are deathly boring…I have tried to break that trend and inject a bit of “life” into the subject. Apparently, according to one of my editors and my graphic designer, I have succeeded, and this is where you, my forum friends and lurkers can give me a massive helping hand.

  • Firstly, please buy a copy (I make about US$1.30 per copy whether it is paperback ($9.99 or ebook $2.99) – at worst, even if you don’t enjoy it, look at it as a donation for all the work I have done on this forum J . The ebook is available on Kindle, Kobo and most other ereaders in major markets (US, UK, Canada EU etc…it should even come to ibooks before too long as well). The paperback is more costly as it is print on demand, so the per unit production is the majority of the price. It is available at Amazon globally, and should be available in all other major on-line book stores within the next few days.
  • Secondly, if you buy it and enjoy it please please recommend it to all your friends through social media and write a positive review on the platform from which you bought it, giving some details as to why you enjoyed it. Without this it will flop and all the time and money that I have put into it will be for nothing…but more importantly, the truth about our origins will remain buried under the layers of fake news and misinformation that is propagated on this subject by the media and even scientists (examples given). If you hate it, PM me through the contact page as to why…please don’t post a nasty review…it may kill it. Likewise, if you find an error, please PM me.

Lastly the name…yes that is my real name on the cover, Ben Williams was the main protagonist in a novel I wrote years ago called Deadly Medicine. I have mentioned before that Ben is not my real name…so I’m sorry if you missed that and are disappointed that my real name is Orson Wedgwood. It may be that because of another blog I have set up, I may need to change my posting name here to Orson.

On that last point. This blog is about NDEs and specifically research into NDEs. It will remain that, and in fact I will become more active again as time goes by as I already have a working draft for a book that I will be writing on the subject. That working draft is Aware of Aware, but it is a bit rubbish and needs updating…when that is complete many of the regular contributors on here may recognize some of the things they have said since they help inform me and others. With that in mind…get me motivated to get on with that…buy a copy of DNA: the elephant in the lab and make me feel appreciated!

Links to the book at amazon.com are below but searching for “DNA elephant in the lab” on any  book retailer globally, including your local amazon market, should work as well:

amazon US paperback link

amazon US kindle link

Thank you reading this far, and apologies if it was off topic…there will be one more post on this in a few weeks time, but otherwise, back to NDEs!!!

Why all this is so important

Apologies for not taking part in the discussions of late but the reasons will become apparent as you read on.

As regulars of this blog will know, my father had been suffering from Alzheimer’s for a number of years, and that in itself poses questions that we have discussed on here regarding what happens to the conscious person during the slow decaying of the brain. What happens to the memories…are they lost forever or stored in some “central repository” outside of this dimension? Of course we have absolutely no idea other than some of the insights that have been gleaned from various subjective NDE reports over the years. Which brings me on to a very personal NDE report, very close to home.

Usually we focus on the science of NDEs and what evidence we have either way, but today I am going to tell you about the NDE that first got me interested in this subject when I was 13 years old. My father was an honest man. He hated lying, and other than Santa, as far as I know he never lied to me about anything, which makes his NDE account the one that holds the most validity to me. He told me that when he was about 9 years old he got knocked off his bike by a car. Suddenly he was above the scene watching people running towards the boy sprawled on the ground in front of the car. The next thing he remembered was being in a beautiful field. It was warm, and the colors were magically vibrant, and there were flowers like he had never seen. At the end of the field was a brilliant figure in white with his arms open. He was drawn towards the figure, but before he reached him (or her), he was suddenly back in his body and awake.

Last week my father passed on…to a better place. I can say that with absolute confidence, not just because of my personal faith but because of his and countless other NDE reports that have so much consistency in terms of fundamental content, that I do not need the results of AWARE II to believe that they are real. I am certain that our inner beings survive death and enter an eternal place of incomparable beauty, and into fellowship with others that is beyond any relationship we ever experience in this physical world.

Finally, the other reason that I have been “off the grid” is that in the little spare time I’ve had, I have been sorting out the internal design and cover of my book on the Origins of DNA and Life. It should be available next week, and of course I will let my friends on this forum know. You will also learn my real name as well (although I think some have already connected another blog with this, which I am just putting together, so may already know).

 

 

Update on AWARE II study:

Thanks to Samwise for this find. The event took place back in September, but the video has only just surfaced. Fast forward to 35 mins in to see Dr Parnia’s talk.

 

Firstly, while there are lots of interesting tidbits, particularly his discussion on the fact that NDEs occur during the period when the brain is least active, there is no “news” regarding evidence of the nature of NDEs. Much of the talk is a summary of the progress so far that has been discussed on this site, and others in great detail. The setting is much improved over the TV studio though, as this is an academic conference.

Dr Parnia does however give the most detailed update yet of the design of the AWARE II study, the number of sites involved, the anticipated timelines and current numbers recruited.

So here we have a picture of the equipment setup:

 

In addition to the cerebral oximetry equipment that will be used to measure flow of oxygen to the brain, we have audio stimulation, which includes putting headphones on the patient (need to watch again to confirm that one) AND the all important iPad. This is the potential game changer.

This is the recruitment status as of March this year before they ramped up the number of sites. This is real news:

4FB85277-2172-4ED7-BFF5-51926A89BB01

At that stage they had 38 patients make it to the end zone. Of those, past research would predict that 3-4 were able to recall NDEs, and if OBEs are real I would estimate 1-2 may have seen an image.

The study is expected to end in 2020, and maybe it will be at this conference that he will present initial results with a more complete dataset published in a serious journal later.

There is quite a bit more in the video worthy of further discussion, but I am on a weekend break, and not able to expand on this just at the moment, but I am sure it will be picked up by the regulars on here who make such valuable contributions…none more so than Samwise!

Brain damage and personality change: evidence against the existence of a separate soul?

Yesterday afternoon I was sitting in front of my father in his nursing home. He has advanced Alzheimer’s disease. He looks at me with his big sad brown eyes, and I know that he hasn’t got a clue who I am. He can’t speak, but he looks around curiously and he smiles…in fact oddly, he smiles more than he used to, and what I can say is that he is most definitely not the same “person” that I have known all my life. There are traces of the “person” but much of it has gone or changed, and yet he is still there, alive.

This kind of scenario is something I have thought about before with respect to NDEs and forms the basis of a legitimate objection to the belief that NDEs are evidence that the soul is separate from the brain (Chad bought this up once in one of our discussions). The argument goes something like this: if the soul is separate from the brain then when the brain is injured through trauma or disease the “personality” should not change as it is not a “function” of the brain. So this invites the question:

Are Personality and the Soul the same thing?

This is very important for trying to get to the bottom of this question, and to be honest it will not be covered fully in this post. I have actually moved countries recently, from Canada back to the UK, due to my parent’s poor health, and in the process I have changed jobs. I am now working in research in obesity (which is ironic as I am not slim!) and in particular on a drug that targets a receptor on a neuron in the hypothalamus which regulates appetite. I am therefore having to learn a lot more about neurotransmitters and how they affect behavior. People who have genetic defects that result in defects in the pathway I am working on, experience extreme hunger…all of the time, even after they have eaten. This then drives their behavior and the behaviors we observe are what we may perceive as personality…we make judgments, that person has no self-control.

Some people who have brain damage can become much angrier. Again, this affects our perception of their personality. Often they experience more extreme ranges of emotions, since emotions are often the result of hormone changes regulated in the brain. Much of this is what defines our personality, and it is absolutely, without doubt, the result of processes in our brain. But is it our soul? Are the soul and personality the same thing and if so, is the brain therefore producing our soul?

I have my thoughts on this, and one piece of anecdotal evidence that might help us understand this better is from NDE accounts. When people leave their bodies and look at themselves, they often “feel” nothing for the body. People often describe being in a peaceful or observant state as though emotions have all but disappeared. Not all though, as some report fear as well. However, in general people appear to be more “objective” in an NDE, as opposed to subjective when inside your body experiencing “life”. I’m not quite sure how, but I feel this may go some way towards answering the question about personality and soul.

I’d be interested in other’s thoughts on this as it is a really tricky question.

With regard to my father, I have tried to rationalize his situation to align with my beliefs. Specifically I believe that the destruction of large parts of his brain from a disease, has resulted in a massively reduced capacity of his soul to “interact” with his brain, resulting in some of the changes I see. Moreover, if some NDE reports are to be believed, then memory is not actually stored in the brain, but in some “central universal repository” and if this is the case, then perhaps my father’s ability to access that repository has gone. Of course, this is me squishing observations into my belief system, and I fully accept that this “understanding” is totally subjective.

Either way, brain damage causes carnage for those who suffer it and those who love them.

Evidence vs “Bullshit”

I promised I would address this particular publication in a new post, as it has got lost in a long and winding discussion that came out of the last post. Here is the link to the full text of the publication which was published in August this year:

Link to PDF of paper on Researchgate

And here is a link to the kind of media interpretation that this article invoked:

Wired – Turns out near-death experiences are psychedelic, not religious

Or the BBC

DMT trip feels like dying

The paper was written by a group of researchers from Imperial College London. Imperial is a premier research institution, so anything that comes out of it should be taken seriously even when it is published in Frontiers of Psychology, a less than premier journal. However, in spite of the source of the research, namely Imperial, the tone that at least one of the researchers adopts towards NDE experiences reveals a distinctly unscientific approach.

“But it’s bullshit. It’s classic pseudoscience,” says Robin Carhart-Harris, who designed the Psychedelic Research Group study with Chris.

This was a reference to Eben Alexander’s book and claims. Now I am not a wild fan of Alexander’s NDE account, and the publicity it generated, but to dismiss it as “bullshit” shows a chronic bias against the possibility that NDEs are a “supernatural” or genuinely religious phenomenon. If you start a research project with that assumption, then you are unlikely to draw unbiased conclusions.

To be fair, the paper itself does not read as badly as it might given the tone of the author in the interview. The study was designed to assess the similarity between the experience of taking the psychedelic drug DMT, with an NDE. To do this they used the Greyson scale, the scale devised by one of the fathers of NDE research, which includes 15 different elements most commonly associated with NDEs. These include tunnels, bright light OBE etc etc. They assessed how much overlap there was in terms of level of experience and range. Their findings revealed that DMT induced an experience which bore similarities to an NDE, with significant overlap on Greyson scores compared to previously published data on those who had experienced actual NDEs. There were a few exceptions, such as less reported life reviews, no point of no return etc, but in general many of the elements of NDEs were reported by subjects taking DMT.

While the original paper does not go so far as to say that this proves that NDEs are hallucinations induced by the release of various hormones and neurotransmitters in the brain at the time of dying, this is most definitely the tone adopted by the Wired article, and certainly appears to be what at least one of the authors believes.

I view things differently. While it is obvious there are some similarities between the two experiences, there are some important differences, some of which I briefly alluded to above. The lack of the kind of detailed life reviews that NDE experiencers report when compared with these DMT induced experiences is significant. If someone is about to potentially die, and a life review is a part of that process, then it makes sense that someone who is not close to death would not have one. This in some ways, using a bit of twisted logic, provides a bit of validation of the fact that NDEs are real. But you could only draw that conclusion if you viewed the research produced by this group through the biased lens that we believers view things.

The truth is, that you could interpret the data from this study in two completely different ways according to your own world view, and both interpretations would be consistent with the findings of the study.

As a reminder, the essence of the key finding was that taking DMT induces an experience which has significant similarity to an NDE.

The first way you could interpret this data is the way in which Wired magazine and the author have – namely that due to this similarity, this shows that NDEs are just a psychedelic experience produced entirely by the chemical activity of the brain.

The other way that that the data could be interpreted is that DMT disrupts the “anchoring” mechanism of the consciousness to the brain, and thereby causes temporary erratic separations of the conscious from the physical brain, but while the patient is alive and fully technically conscious. Here is a quote from one of the subjects:

“It’s probably the most intense experience I’ve had,” says Iona. “[The sense that] birth and death were just a transformation rather than an end was something that felt true.”

It is entirely consistent with the data from the study to suggest that DMT could indeed cause just the kind of disruption that I describe above. If the brain is just a host of the conscious then pumping a brain full of a drug that is neurotoxic may indeed cause the association with the brain to loosen, and for that conscious to briefly dip into “other realms”. The researcher dismisses this idea out of hand, but provides no rationale for making that assertion.

Ultimately, the evidence from this study is valid, but the conclusions drawn by the researchers themselves in the interview and the media may indeed be “bullshit”, and entirely the result of atheistic bias. At the end of the day, the study, while intriguing, is a great big “nothing burger” in terms of providing evidence that NDEs are not a “supernatural” phenomenon.

The Illusive Dr Parnia Tweets

Thanks to one of the regular contributors for this reminder, but Dr Parnia tweeted for the first time in a very long time:

parnia tweet

I use the word illusive since he doesn’t really clarify what this means. Is this AWARE II, surely not as that is well under way now. Are these sub-studies of AWARE II? Are they completely new studies, and if so how will they differ?

Anyway, hopefully we will learn more before long.

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