We come to that time of the year again when we look back at the past year and rue the lack of new data, and look forward hoping that this year will be different. We are like the characters in the 1980s UK hit TV show, Only Fools and Horses featuring Del Boy and Rodney Trotter, who lived in a state apartment in a poor part of London and were always coming up with schemes to make themselves rich, but never succeeding. “This time next year Rodney,” Del boy would say to his younger brother, “we’ll be millionaires.” It was either this analogy I was going to use, or Groundhog Day…both fit the feeling I have about the AWARE II study despite the promising Tweet made just after New Years which stated:
“We hope to see you in 2022 as we ring in the New Year with exciting news, including updates on the AWARE II study!“
This has been followed more recently by some Tweets on the study that looks into paradoxical terminal lucidity in patients with Dementia. I currently work in Dementia as a medical scientist for a Biotech with “skin in the game” so to speak. Also, I watched my father die from Dementia, so I am very interested in this study. I have spoken about this in previous posts, so won’t say any more for now.
On the promise of “updates on the AWARE II study” I am now very cautious about raising my hopes too much having experienced so much disappointment over the years. My expectations range from a statement saying they have more hospitals recruiting patients, to a paper, or conference abstract that provides more details on the different auditory experiences they reported at AHA 2019. The latter has the potential to be extremely important, although I doubt the media or wider scientific community will regard it in such a light. It is clear that Parnia does not believe that CPRIC (CPR induced consciousness) or blood flow from CPR could produce NDEs. I was not certain of this until I read the essay that he submitted to the Bigelow competition (more on that in a moment). It is possible that the update from the AWARE II study includes data from EEG and ECG matched against one or more of the reported auditory OBEs. This could be the smoking gun. Like I said, the scientific community may not accept it as such without a lot of persuasion.
The Tweet trailing “exciting news” was not just confined to the AWARE II study though. It is possible that data may be presented from AWARE III, the study looking into OBEs reported during hypothermic surgery. They recruited their first patient in August 2020, and it is possible that they have been recruiting a number each month, and if that were the case, I would fully expect to have a hit by now.
Who knows, but watch this space, or sign up directly to their Twitter feed.
On another note, I was able to read Sam Parnia’s essay over the Christmas holidays. It was a robust defense of the argument supporting NDEs and as well as going over a lot of old ground, I feel he made a lot more of the hit from AWARE I than he previously has, specifically stating that this is the only time in a clinical study that recollections from an NDE have been corroborated by attending HCPs AND that these recollections were time stamped to prove that they were from a time that the patient had no heartbeat. In some ways this made me feel a little concerned that this would be his “forever hit”, and that from his standpoint no more evidence is needed. From a proof standpoint, I somewhat agree, but then I would, it’s the wider scientific community that demands more.
He also provided a very good argument, supported by data, that CPR could not produce the lucid kind of experiences described in NDEs as CPR does not produce sufficient blood flow, and the EEG patterns associated with CPR do not correspond to consciousness. As others have noted in previous discussions, this puts to bed any doubts around CPR causing the auditory OBEs in AWARE II despite this going against the line that he put in his AHA abstract, so I look forward to any publication that goes into this further. He also discussed CPRIC which is a completely different phenomenon, and is when the patient achieves consciousness during CPR, normally as a result of brief restoration of heart beat. This kind of event is always associated with confusion and distress, and completely different from the kind of recollections that feature in an NDE.
Anyway, I will once again draw deep on my reserves of hope that we will learn of that illusive hit before too long. To me it is inevitable, and judging by the Tweets, the Parnia team also believe it is inevitable, otherwise why would they be so assertive in claiming that CA survivors can recall details from the time they were beyond the threshold of death?